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MRD in Acute Leukemias: Lessons Learned from Acute Promyelocytic Leukemia

20 Sept 2024

Abstract excerpt

Introduction: Advances in molecular biology, polymerase chain reaction (PCR), and next-generation sequencing (NGS) have transformed the concept of minimal residual disease (MRD) from a philosophical idea into a measurable reality. Current Treatment Paradigms and Lessons Learned from APL: Acute promyelocytic leukemia (APL) leads the way in this transformation, initially using PCR to detect MRD in patients in...

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PMID: 39335179
DOI: 10.3390/cancers16183208

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