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Article

Characterization of a Novel Tripartite Nuclear Localization Sequence in the EGFR Family

6 Feb 2007

Abstract excerpt

Aberrant expression of epidermal growth factor receptor (EGFR) is present in many human tumors. Several reports have shown that EGFR is translocated into the nucleus during liver regeneration and in several types of cells and tissues such as placenta and thyroid. Nuclear EGFR is associated with transcription, DNA synthesis, and DNA repair activity and serves as a prognostic marker in breast carcinoma and...

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Identifiers

PMID: 17283074
DOI: 10.1074/jbc.m610014200

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