Article
Integrative analysis of a cancer somatic mutome.
Molecular cancer - 5 Feb 2007
Hernández Pilar, Solé Xavier, Valls Joan, Moreno Víctor, Capellá Gabriel, Urruticoechea Ander, Pujana Miguel Angel
Abstract excerpt
BACKGROUND: The consecutive acquisition of genetic alterations characterizes neoplastic processes. As a consequence of these alterations, molecular interactions are reprogrammed in the context of highly connected and regulated cellular networks. The recent identification of the collection of somatically mutated genes in breast tumors (breast cancer somatic "mutome") allows the comprehensive study of its function...
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