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Breast cancer genomics from microarrays to massively parallel sequencing: paradigms and new insights.

Journal of the National Cancer Institute - 23 Feb 2015

Ng Charlotte K Y, Schultheis Anne M, Bidard Francois-Clement, Weigelt Britta, Reis-Filho Jorge S

Abstract excerpt

Rapid advancements in massively parallel sequencing methods have enabled the analysis of breast cancer genomes at an unprecedented resolution, which have revealed the remarkable heterogeneity of the disease. As a result, we now accept that despite originating in the breast, estrogen receptor (ER)-positive and ER-negative breast cancers are completely different diseases at the molecular level. It has become...

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PMID: 25713166
DOI: 10.1093/jnci/djv015

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GATA3

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