Article
Drosophila melanogaster Thor and response to Candida albicans infection.
Eukaryotic cell - 1 Apr 2007
Levitin A, Marcil A, Tettweiler G, Laforest M J, Oberholzer U, Alarco A M, Thomas D Y, Lasko P, Whiteway M
Abstract excerpt
We used Drosophila melanogaster macrophage-like Schneider 2 (S2) cells as a model to study cell-mediated innate immunity against infection by the opportunistic fungal pathogen Candida albicans. Transcriptional profiling of S2 cells coincubated with C. albicans cells revealed up-regulation of several genes. One of the most highly up-regulated genes during this interaction is the D. melanogaster translational...
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