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Article

RNA Enrichment Method for Quantitative Transcriptional Analysis of Pathogens <i>In Vivo</i> Applied to the Fungus Candida albicans

23 Sept 2015

Abstract excerpt

UNLABELLED: In vivo transcriptional analyses of microbial pathogens are often hampered by low proportions of pathogen biomass in host organs, hindering the coverage of full pathogen transcriptome. We aimed to address the transcriptome profiles of Candida albicans, the most prevalent fungal pathogen in systemically infected immunocompromised patients, during systemic infection in different hosts. We developed a...

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PMID: 26396240
DOI: 10.1128/mbio.00942-15

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