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Article

Drosophila Thor participates in host immune defense and connects a translational regulator with innate immunity.

Proceedings of the National Academy of Sciences of the United States of America - 23 May 2000

Bernal A, Kimbrell D A

Abstract excerpt

Thor has been identified as a new type of gene involved in Drosophila host immune defense. Thor is a member of the 4E-binding protein (4E-BP) family, which in mammals has been defined as critical regulators in a pathway that controls initiation of translation through binding eukaryotic initiation factor 4E (eIF4E). Without an infection, Thor is expressed during all developmental stages and transcripts localize to...

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Identifiers

PMID: 10811906
DOI: 10.1073/pnas.100391597
PMCID: PMC18551

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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