Article
Combination of angiotensin-converting enzyme and methylenetetrahydrofolate reductase gene polymorphisms as determinant risk factors for chronic allograft dysfunction.
Transplantation proceedings - 1 Jan 2000
de Alvarenga M P S, Pavarino-Bertelli E C, Abbud-Filho M, Ferreira-Baptista M A S, Haddad R, Eberlin M N, Goloni-Bertollo E M
Abstract excerpt
OBJECTIVE: The aim of this study was to investigate the frequency of gene angiotensin-converting enzyme insertion/deletion (ACE I/D) and methylenetetrahydrofolate reductase (MTHFR C677T and A1298C) variants, as well as to evaluate the plasma homocysteine concentrations in 217 patients who underwent renal transplantation at least 12 months prior to define risk factors for chronic allograft dysfunction. METHODS:...
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