Article
The effect of angiotensin converting enzyme gene polymorphism on chronic allograft dysfunction in living donor renal transplant recipients.
Clinical transplantation - 1 Jun 2002
Yildiz Alaattin, Yazici Halil, Cine Naci, Akkaya Vakur, Kayacan S Mehmet, Sever Mehmet Sükrü, Erginel-Unaltuna Nihan
Abstract excerpt
BACKGROUND: Chronic allograft dysfunction (CAD), the major cause of the failure of kidney allografts, may be caused by immunological and non-immunological haemodynamic factors. Renin-angiotensin system has been implicated in the development of intraglomerular hypertension and has a central role on progression in chronic renal disease. Polymorphism in 16th intron of the ACE gene has been reported to predict the...
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