Article
Effect of folate, vitamin B6, and vitamin B12 intake and MTHFR C677T polymorphism on homocysteine concentrations of renal transplant recipients.
Transplantation proceedings - 1 Dec 2007
Biselli P M, Sanches de Alvarenga M P, Abbud-Filho M, Ferreira-Baptista M A S, Galbiatti A L S, Goto M T Y, Cardoso M A, Eberlin M N, Haddad R, Goloni-Bertollo E M, Pavarino-Bertelli E C
Abstract excerpt
Plasma hyperhomocysteinemia (HHcy) is considered a risk factor for chronic allograft dysfunction (CAD), the main cause of functional loss in transplant recipients. Genetic polymorphisms that alter enzymes involved in homocysteine (Hcy) metabolism, such as methylenetetrahydrofolate reductase (MTHFR), and vitamin deficiency can result in HHcy. The objectives of this study were to investigate the relationship...
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