Article
Genetic predisposition and renal allograft failure: implication of non-HLA genetic variants.
Molecular diagnosis & therapy - 1 Jan 2006
Khan Faisal, Agrawal Swati, Agrawal Suraksha
Abstract excerpt
Renal allograft rejection or dysfunction often results in graft failure, and remains the major obstacle in the success of renal transplantation. Various immunological and nonimmunological factors are involved in allograft rejection. In addition to human leukocyte antigen loci, several genetically controlled molecules have been identified in recent years as playing important roles in the process of rejection....
Topics
- Genetic Predisposition to Disease
- Graft Rejection
- HLA Antigens
- Humans
- Immunologic Factors
- Kidney Transplantation
- T-Lymphocytes, Helper-Inducer