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Genome-wide reprogramming in hybrids of somatic cells and embryonic stem cells.

Stem cells (Dayton, Ohio) - 1 May 2007

Ambrosi Dominic J, Tanasijevic Borko, Kaur Anupinder, Obergfell Craig, O'Neill Rachel J, Krueger Winfried, Rasmussen Theodore P

Abstract excerpt

Recent experiments demonstrate that somatic nuclei can be reprogrammed to a pluripotent state when fused to ESCs. The resulting hybrids are pluripotent as judged by developmental assays, but detailed analyses of the underlying molecular-genetic control of reprogrammed transcription in such hybrids are required to better understand fusion-mediated reprogramming. We produced hybrids of mouse ESCs and fibroblasts...

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Identifiers

PMID: 17272499
DOI: 10.1634/stemcells.2006-0532

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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