Article
Mouse embryonal carcinoma cell-somatic cell hybrids as experimental tools for the study of cell differentiation and X chromosome activity.
Cancer genetics and cytogenetics - 1 Jan 1997
Takagi N
Abstract excerpt
Remarkable properties of murine embryonal carcinoma cells, stem cells of teratocarcinomas, manifest themselves when they are fused with differentiated somatic cells. Among others the capacity to reprogram genomes from these somatic cells and restore genetic pluripotency is most striking.
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