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Article

Epidermal Growth Factor Receptor activation promotes ADA3 acetylation through the AKT-p300 pathway.

Cell cycle (Georgetown, Tex.) - 18 Aug 2017

Srivastava Shashank, Mohibi Shakur, Mirza Sameer, Band Hamid, Band Vimla

Abstract excerpt

The ADA3 (Alteration/Deficiency in Activation 3) protein is an essential adaptor component of several Lysine Acetyltransferase (KAT) complexes involved in chromatin modifications. Previously, we and others have demonstrated a crucial role of ADA3 in cell cycle progression and in maintenance of genomic stability. Recently, we have shown that acetylation of ADA3 is key to its role in cell cycle progression. Here,...

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Identifiers

PMID: 28759294
DOI: 10.1080/15384101.2017.1339846
PMCID: PMC5584872

Genes

EGFR
PCNA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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