Genomic profiling of malignant pleural mesothelioma with array‐based comparative genomic hybridization shows frequent non‐random chromosomal alteration regions including <i>JUN</i> amplification on 1p32

Abstract excerpt

Genome-wide array-based comparative genomic hybridization analysis of malignant pleural mesotheliomas (MPM) was carried out to identify regions that display DNA copy number alterations. Seventeen primary tumors and nine cell lines derived from 22 individuals were studied, some of them originating from the same patients. Regions of genomic aberrations observed in >20% of individuals were 1q, 5p, 7p, 8q24 and 20p...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Medical Imaging and Pathology Studies
• Share to Occupational and environmental lung diseases