Article
Large scale genotype-phenotype correlation analysis based on phylogenetic trees.
Bioinformatics (Oxford, England) - 1 Apr 2007
Habib Farhat, Johnson Andrew D, Bundschuh Ralf, Janies Daniel
Abstract excerpt
We provide two methods for identifying changes in genotype that are correlated with changes in a phenotype implied by phylogenetic trees. The first method, VENN, works when the number of branches over which the change occurred are modest. VENN looks for genetic changes that are completely penetrant with phenotype changes on a tree. The second method, CCTSWEEP, allows for a partial matching between changes in...
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