Exploiting naturally occurring DNA variation and molecular profiling data to dissect disease and drug response traits.

Abstract excerpt

Identifying the key drivers of common human diseases and associated signaling pathways remains one of the primary objectives in the biomedical and life sciences. In this respect, common inbred strains of mice have played a crucial role, and recent advances in the development of genomics and bioinformatics tools have significantly enhanced their utility for this purpose. These advances have enabled a more...

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• Algorithms
• Gene Expression Profiling
• Genetic Variation
• Genomics
• Mice
• Pharmaceutical Preparations