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Article

Functional COMT Val158Met polymorphism, risk of acute coronary events and serum homocysteine: the Kuopio ischaemic heart disease risk factor study.

PloS one - 31 Jan 2007

Voutilainen Sari, Tuomainen Tomi-Pekka, Korhonen Maarit, Mursu Jaakko, Virtanen Jyrki K, Happonen Pertti, Alfthan Georg, Erlund Iris, North Kari E, Mosher M J, Kauhanen Jussi, Tiihonen Jari, Kaplan George A, Salonen Jukka T

Abstract excerpt

BACKGROUND: The role of circulating levels of total homocysteine tHcy in the development of coronary heart disease (CHD) is still under debate. One reason for conflicting results between previous studies on homocysteine and heart diseases could be consequence of different interactions between homocysteine and genes in different study populations. Many genetic factors play a role in folate-homocysteine metabolism,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17264883
DOI: 10.1371/journal.pone.0000181
PMCID: PMC1779620

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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