The association between plasma homocysteine and coronary heart disease is modified by the MTHFR 677C>T polymorphism.

doi:10.1136/heartjnl-2013-304460

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Article

The association between plasma homocysteine and coronary heart disease is modified by the MTHFR 677C>T polymorphism.

Heart (British Cardiac Society) - 1 Dec 2013

Mehlig K, Leander K, de Faire U, Nyberg F, Berg C, Rosengren A, Björck L, Zetterberg H, Blennow K, Tognon G, Torén K, Strandhagen E, Lissner L, Thelle D

Abstract excerpt

OBJECTIVE: An elevated level of total plasma homocysteine (tHcy) has been associated with risk of coronary heart disease (CHD). The level of tHcy is affected by lifestyle, in addition to genetic predisposition. The methylene tetrahydrofolate reductase (MTHFR) 677C>T polymorphism (rs1801133) is am...

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PMID: 24014284
DOI: 10.1136/heartjnl-2013-304460

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MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24014284-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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