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Article

Catechol-o-methyltransferase gene polymorphism modifies the effect of coffee intake on incidence of acute coronary events.

PloS one - 27 Dec 2006

Happonen Pertti, Voutilainen Sari, Tuomainen Tomi-Pekka, Salonen Jukka T

Abstract excerpt

BACKGROUND: The role of coffee intake as a risk factor for coronary heart disease (CHD) has been debated for decades. We examined whether the relationship between coffee intake and incidence of CHD events is dependent on the metabolism of circulating catecholamines, as determined by functional po...

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Identifiers

PMID: 17205121
DOI: 10.1371/journal.pone.0000117
PMCID: PMC1762420

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-17205121-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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