Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The role of genetic factors in the development of hyperhomocysteinemia.

Clinical chemistry and laboratory medicine - 1 Nov 2003

Geisel Jürgen, Hübner Ulrich, Bodis Marion, Schorr Heike, Knapp Jean-Pierre, Obeid Rima, Herrmann Wolfgang

Abstract excerpt

Moderate hyperhomocysteinemia has been identified as a new independent risk factor for cardiovascular and neurodegenerative diseases. This fact has produced interest in the study of genetic variants involved in homocysteine metabolism and its relationship to pathogenesis. Recently, more than 15 different genes were studied for their relationship to plasma homocysteine levels. We determined the influence of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Glycine Hydroxymethyltransferase
Share to Catechol O-Methyltransferase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Folic Acid Deficiency

Share to Homocysteine

Share to Hyperhomocysteinemia

Share to Thymidylate Synthase

Share to Transcobalamins

Share to Vitamin B 12 Deficiency

Source

Identifiers

PMID: 14656021
DOI: 10.1515/CCLM.2003.219

Genes

COMT
MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The role of genetic factors in the development of hyperhomocysteinemia.PMID 14656021Read ↗

Genetic and nutritional factors contributing to hyperhomocysteinemia in young adults.Semantic proximity Read ↗

Polymorphism of genes encoding homocysteine metabolism-related enzymes and risk for cardiovascular disease.Semantic proximity Read ↗

Single nucleotide polymorphisms in homocysteine metabolism pathway genes: association of CHDH A119C and MTHFR C677T with hyperhomocysteinemia.Semantic proximity Read ↗

Genetic defects as important factors for moderate hyperhomocysteinemia.Semantic proximity Read ↗

Genetic determinants of plasma total homocysteine.Semantic proximity Read ↗

Genetics of homocysteine metabolism and associated disordersSemantic proximity Read ↗

Genetics of homocysteine metabolism and associated disordersSemantic proximity Read ↗

Plasma homocysteine concentrations in Greek children are influenced by an interaction between the methylenetetrahydrofolate reductase C677T genotype and folate status.Semantic proximity Read ↗

Interaction of Genetics and Dietary Patterns Scored by the High Healthy Eating Index in Hyperhomocysteinaemia Influencing Cardiovascular Disease Risk.Semantic proximity Read ↗

Molecular genetics of homocysteine metabolism.Semantic proximity Read ↗

Polymorphisms in the catechol-O-methyltransferase (COMT) gene influence plasma total homocysteine levels.Semantic proximity Read ↗

The vegetarian lifestyle and DNA methylationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.