Article
Comparison of the lectin-binding pattern in different human melanoma cell lines.
Melanoma research - 1 Jun 2001
Lityńska A, Przybyło M, Pocheć E, Hoja-Łukowicz D, Ciołczyk D, Laidler P, Gil D
Abstract excerpt
Glycosylation is generally altered in tumour cells in comparison with their normal counterparts. These alterations are thought to be important because they contribute to the abnormal behaviour of cancer cells. Therefore, we have comparatively analysed the glycoproteins in cell extracts from human melanoma (primary site--WM35; metastatic sites-- WM239, WM9 and A375) cell lines using sodium dodecyl...
Topics
- Agglutinins
- Blotting, Western
- Cadherins
- Densitometry
- Electrophoresis, Polyacrylamide Gel
- Galanthus
- Glycoproteins
- Glycosylation
- Humans
- Lectins
- Melanoma
- Phenotype
- Plant Lectins
- Protein Binding
- Tumor Cells, Cultured
