Article
Cytokine gene polymorphisms and breast cancer susceptibility.
Annals of the New York Academy of Sciences - 1 Nov 2006
Scola Letizia, Vaglica Marina, Crivello Antonino, Palmeri Laura, Forte Giusi Irma, Macaluso Maria Catena, Giacalone Antonio, Di Noto Laura, Bongiovanni Alberto, Raimondi Cristina, Accardo Angela, Verna Roberto, Candore Giuseppina, Caruso Calogero, Lio Domenico, Palmeri Sergio
Abstract excerpt
Human breast cancer (BC) is characterized by a considerable clinical heterogeneity. Steroid hormone receptor expression and growth factor receptor expression have been considered suitable diagnostic and prognostic markers, whereas mutations of oncosuppressor and gatekeeper genes have been found associated with an increased risk for this malignancy. To evaluate the role that polymorphisms of genes involved in the...
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