Article
Mapping a quantitative trait locus (QTL) conferring pyrethroid resistance in the African malaria vector Anopheles funestus.
BMC genomics - 29 Jan 2007
Wondji Charles S, Morgan John, Coetzee Maureen, Hunt Richard H, Steen Keith, Black William C, Hemingway Janet, Ranson Hilary
Abstract excerpt
BACKGROUND: Pyrethroid resistance in Anopheles funestus populations has led to an increase in malaria transmission in southern Africa. Resistance has been attributed to elevated activities of cytochrome P450s but the molecular basis underlying this metabolic resistance is unknown. Microsatellite and SNP markers were used to construct a linkage map and to detect a quantitative trait locus (QTL) associated with...
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