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Article

Two duplicated P450 genes are associated with pyrethroid resistance in Anopheles funestus, a major malaria vector.

Genome research - 1 Mar 2009

Wondji Charles S, Irving Helen, Morgan John, Lobo Neil F, Collins Frank H, Hunt Richard H, Coetzee Maureen, Hemingway Janet, Ranson Hilary

Abstract excerpt

Pyrethroid resistance in Anopheles funestus is a potential obstacle to malaria control in Africa. Tools are needed to detect resistance in field populations. We have been using a positional cloning approach to identify the major genes conferring pyrethroid resistance in this vector. A quantitative trait locus (QTL) named rp1 explains 87% of the genetic variance in pyrethroid susceptibility in two families from...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 19196725
DOI: 10.1101/gr.087916.108
PMCID: PMC2661802

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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