Article
Directionally selected cytochrome P450 alleles are driving the spread of pyrethroid resistance in the major malaria vector Anopheles funestus.
Proceedings of the National Academy of Sciences of the United States of America - 2 Jan 2013
Riveron Jacob M, Irving Helen, Ndula Miranda, Barnes Kayla G, Ibrahim Sulaiman S, Paine Mark J I, Wondji Charles S
Abstract excerpt
Pyrethroid insecticides are critical for malaria control in Africa. However, resistance to this insecticide class in the malaria vector Anopheles funestus is spreading rapidly across Africa, threatening the success of ongoing and future malaria control programs. The underlying resistance mechanisms driving the spread of this resistance in wild populations remain largely unknown. Here, we show that increased...
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