Article
Genetic mapping of genes conferring permethrin resistance in the malaria vector, Anopheles gambiae.
Insect molecular biology - 1 Aug 2004
Ranson H, Paton M G, Jensen B, McCarroll L, Vaughan A, Hogan J R, Hemingway J, Collins F H
Abstract excerpt
Resistance to permethrin in an East African population of the major malaria vector, Anopheles gambiae is multifactorial. A mutated sodium channel allele and enhanced insecticide metabolism contribute to the resistance phenotype. We used microsatellite markers to scan the genome for quantitative trait loci (QTL) associated with permethrin resistance. Two major and one minor QTL were identified. The first QTL,...
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