Article
Genetic modulation of adenosine receptor function and adenosine handling in murine hearts: insights and issues.
Journal of molecular and cellular cardiology - 1 Apr 2007
Ashton Kevin J, Peart Jason N, Morrison R Ray, Matherne G Paul, Blackburn Michael R, Headrick John P
Abstract excerpt
The adenosine receptor system has been attributed with a broad range of both physiological and so-called 'retaliatory' functions in the heart and vessels. Despite many years of research, the precise roles of adenosine within the cardiovascular system continue to be debated, and new functions are continually emerging. Adenosine acts via 4 known G-protein-coupled receptor (GPCR) sub-types: A(1), A(2A), A(2B), and...
Topics
- Adenosine
- Animals
- Cardiovascular Diseases
- Heart
- Mice
- Phenotype
- Receptors, Purinergic P1
