Article
A GAS-like gene family in the pathogenic fungus Candida glabrata.
Microbiology (Reading, England) - 1 Aug 2001
Weig Michael, Haynes Ken, Rogers Thomas R, Kurzai Oliver, Frosch Matthias, Mühlschlegel Fritz A
Abstract excerpt
In fungi, the cell wall plays a major role in host-pathogen interactions. Despite this, little is known about the molecular basis of cell wall assembly in Candida glabrata, which has emerged as the second most common cause of systemic candidosis. A C. glabrata gene family, CgGAS1-3, that shares significant homologies with both the GAS1 gene of Saccharomyces cerevisiae, which is necessary for cell wall assembly,...
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