Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Complement and c4 null alleles in severe chronic adult periodontitis.

Scandinavian journal of immunology - 1 Feb 2007

Seppänen M, Lokki M-L, Notkola I-L, Mattila K, Valtonen V, Nieminen A, Vesanen M, Asikainen S, Meri S

Abstract excerpt

Severe forms of chronic periodontitis affect up to 10% of adults. Tumour necrosis factor and lymphotoxin-alpha genes in the major histocompatibility complex are associated with severe periodontitis. Complement factor C4 is a nearby, polymorphic, functionally relevant gene region. Although associated with chronic mucosal infections, C4 deficiencies have not been assessed in adult periodontitis patients. We tested...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to Alleles
Share to Chronic Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Complement C4

Share to Genetic Predisposition to Disease

Share to Periodontitis

Source

Identifiers

PMID: 17257223
DOI: 10.1111/j.1365-3083.2006.01886.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Complement and c4 null alleles in severe chronic adult periodontitis.PMID 17257223Read ↗

Complement and periodontitis.Semantic proximity Read ↗

Common complement factor H polymorphisms are linked with periodontitis in elderly patients.Semantic proximity Read ↗

The complement system and its role in the pathogenesis of periodontitis: current conceptsSemantic proximity Read ↗

SNPs of Fc-gamma receptor genes and chronic periodontitis.Semantic proximity Read ↗

No association between selected candidate gene polymorphisms and severe chronic periodontitis.Semantic proximity Read ↗

Fibroblast derived C3 promotes the progression of experimental periodontitis through macrophage M1 polarization and osteoclast differentiationSemantic proximity Read ↗

Using genetics to explore complement C5 as a druggable protein in periodontitis.Semantic proximity Read ↗

Single nucleotide polymorphisms of complement component 5 and periodontitis.Semantic proximity Read ↗

Complement genetics and host defence.Semantic proximity Read ↗

Complement split product C3c in saliva as biomarker for periodontitis and response to periodontal treatmentSemantic proximity Read ↗

Association of the -159 CD14 gene polymorphism and lack of association of the -308 TNFA and Q551R IL-4RA polymorphisms with severe chronic periodontitis in Swedish Caucasians.Semantic proximity Read ↗

Lack of association between chronic periodontitis and the Toll-like receptor 4 gene polymorphisms in a Czech population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.