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Article

The complement system and its role in the pathogenesis of periodontitis: current concepts

5 Jul 2014

Abstract excerpt

Periodontitis is a highly prevalent inflammatory disease in tooth supporting tissues, induced by bacteria growing in a biofilm on tooth surfaces. Components of the complement system are present in the periodontal tissue and the system is activated in periodontitis. Continuous complement activation and modulation by bacteria within the biofilm in periodontal pockets, however, may enhance local tissue destruction,...

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PMID: 25040158
DOI: 10.1111/jre.12209

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