Article
Association of the -159 CD14 gene polymorphism and lack of association of the -308 TNFA and Q551R IL-4RA polymorphisms with severe chronic periodontitis in Swedish Caucasians.
Journal of clinical periodontology - 1 May 2005
Donati Mauro, Berglundh Tord, Hytönen Ann-Marie, Hahn-Zoric Mirjana, Hanson Lars-A, Padyukov Leonid
Abstract excerpt
BACKGROUND: Severe forms of periodontitis are suggested to have a genetic basis. OBJECTIVE: The aim of the present investigation was to study the association of gene polymorphisms related to some immune regulation components (G-308A TNFA, Q551R IL-4RA and C-159T CD14) with severe chronic periodontitis. MATERIALS AND METHODS: Sixty patients (aged 36-74 years; mean 54.5+/-8.5) with severe and generalized chronic...
Topics
- Adult
- Aged
- Alleles
- Alveolar Bone Loss
- Case-Control Studies
- Chronic Disease
- Female
- Gene Frequency
- Humans
- Lipopolysaccharide Receptors
- Male