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Article

MYH, OGG1, MTH1, and APC alterations involved in the colorectal tumorigenesis of Korean patients with multiple adenomas.

Virchows Archiv : an international journal of pathology - 1 Mar 2007

Kim Jin C, Ka In H, Lee Yoo M, Koo Kum H, Kim Hee C, Yu Chang S, Jang Se J, Kim Yong S, Lee Han I, Lee Kang H

Abstract excerpt

This study was done to characterize base excision repair (BER) genes and adenomatous polyposis coli (APC) alterations in the tumorigenesis of multiple colorectal adenomas in Korean patients. In total, 217 adenomas (mean number = 10) and 117 cancers were available from 143 patients. The heterozygous genotype of OGG1 c.1-18G>T was closely associated with multiple adenoma families (P < 0.001), while MYH A359V...

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Source

Identifiers

PMID: 17252231
DOI: 10.1007/s00428-006-0363-6

Genes

APC
OGG1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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