Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Integrative Transcriptome and Proteome Analyses Elucidate the Mechanism of Lens-Induced Myopia in Mice

11 Oct 2023

Abstract excerpt

Purpose: The purpose of this study was to investigate the underlying molecular mechanism of lens-induced myopia (LIM) through transcriptome and proteome analyses with a modified mouse myopia model. Methods: Four-week-old C57BL/6J mice were treated with a homemade newly designed -25 diopter (D) lens mounting by a 3D printing pen before right eyes for 4 weeks. Refraction (RE) and axial dimensions were measured...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Connexins and lens biology
Share to Intraocular Surgery and Lenses
Share to Ophthalmology and Visual Impairment Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37819745
DOI: 10.1167/iovs.64.13.15

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Integrative Transcriptome and Proteome Analyses Elucidate the Mechanism of Lens-Induced Myopia in MicePMID 37819745Read ↗

Shedding light on myopia by studying complete congenital stationary night blindness.Semantic proximity Read ↗

Integrated Comparison of GWAS, Transcriptome, and Proteomics Studies Highlights Similarities in the Biological Basis of Animal and Human Myopia.Semantic proximity Read ↗

Bidirectional Expression of Metabolic, Structural, and Immune Pathways in Early Myopia and HyperopiaSemantic proximity Read ↗

Gut microbiome and plasma metabolome alterations in myopic miceSemantic proximity Read ↗

Applications of Genomics and Transcriptomics in Precision Medicine for Myopia Control or PreventionSemantic proximity Read ↗

The retina/RPE proteome in chick myopia and hyperopia models: Commonalities with inherited and age-related ocular pathologies.Semantic proximity Read ↗

Genome-Wide Scleral Micro- and Messenger-RNA Regulation During Myopia Development in the MouseSemantic proximity Read ↗

Genome-Wide Association Analysis Identifies LILRB2 Gene for Pathological Myopia.Semantic proximity Read ↗

Transcriptome‐based insights into gene networks controlling myopia preventionSemantic proximity Read ↗

Analysis of genetic networks regulating refractive eye development in collaborative cross progenitor strain mice reveals new genes and pathways underlying human myopiaSemantic proximity Read ↗

Analysis of genetic networks regulating refractive eye development in collaborative cross progenitor strain mice reveals new genes and pathways underlying human myopiaSemantic proximity Read ↗

Cross-tissue dual-omics analysis reveals molecular programs linked to myopia susceptibility and progression.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.