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Article

DNA diagnostics by surface-bound melt-curve reactions.

The Journal of molecular diagnostics : JMD - 1 Feb 2007

Strömqvist Meuzelaar Linda, Hopkins Katie, Liebana Ernesto, Brookes Anthony J

Abstract excerpt

Melting-curve procedures track DNA denaturation in real time and so provide an effective way of assessing sequence variants. Dynamic allele-specific hybridization (DASH) is one such method, based on fluorescence, which uses heat to denature a single allele-specific probe away from one strand of a polymerase chain reaction product attached to a solid support. DASH is a proven system for research genotyping, but...

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Identifiers

PMID: 17251333
DOI: 10.2353/jmoldx.2007.060057
PMCID: PMC1867427

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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