Article
Relationship between the thromboxane A2 receptor gene and susceptibility to cerebral infarction.
Hypertension research : official journal of the Japanese Society of Hypertension - 1 Sept 2006
Kaneko Yoshiyuki, Nakayama Tomohiro, Saito Kosuke, Morita Akihiko, Sato Ichiro, Maruyama Aya, Soma Masayoshi, Takahashi Teruyuki, Sato Naoyuki
Abstract excerpt
The risk of cerebral infarction (CI) in an individual is dependent on the interplay between genetic risk factors and environmental influences. Binding of thromboxane A2 (TXA2) to its receptor (TP) modulates thrombosis/hemostasis and plays a significant role in the pathogenesis of CI. The aim of the present study was to investigate the relationship between human TP gene single nucleotide polymorphisms (SNPs) and...
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