Article
Thromboxane A2 receptor polymorphism in association with cerebral infarction and its regulation on platelet function.
Current neurovascular research - 1 Jan 2015
Shao Jiaxiang, Fu Yi, Yang Wanlin, Yan Jing, Zhao Jing, Chen Shengdi, Xia Weiliang
Abstract excerpt
Binding of thromboxane A2 (TXA2) to its receptor TXA2R modulates thrombosis/hemostasis and plays a vital role in the pathogenesis of cerebral infarction (CI). In this study, we investigated the relationship between TXA2R polymorphisms and CI in Chinese Han population and the effect on platelet function by these polymorphisms. Polymerase chain reaction and ligase detection reaction (PCR-LDR) was performed in 230...
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