Article
Diagnostic and Prognostic Implications of FGFR3high/Ki67high Papillary Bladder Cancers.
International journal of molecular sciences - 28 Aug 2018
Geelvink Mirja, Babmorad Armin, Maurer Angela, Stöhr Robert, Grimm Tobias, Bach Christian, Knuechel Ruth, Rose Michael, Gaisa Nadine T
Abstract excerpt
Prognostic/therapeutic stratification of papillary urothelial cancers is solely based upon histology, despite activated FGFR3-signaling was found to be associated with low grade tumors and favorable outcome. However, there are FGFR3-overexpressing tumors showing high proliferation-a paradox of coexisting favorable and adverse features. Therefore, our study aimed to decipher the relevance of...
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