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Article

Expression of human PTPN22 alleles.

Genes and immunity - 1 Mar 2007

Nielsen C, Barington T, Husby S, Lillevang S T

Abstract excerpt

Considering the female predominance in most of the autoimmune disorders that associate with the PTPN22 Trp620 variant and the complexity by which this variant influences immunologic tolerance, the objective of this study was to ascertain if the allele-specific expression of the disease-associated Arg620Trp polymorphism is affected by cis-acting or sex-specific trans-acting factor/s (e.g. sex-hormones). The use of...

Read the complete abstract on PubMed

Topics

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Share to Amino Acid Substitution
Share to Autoimmune Diseases
Share to Electrophoresis, Capillary

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Leukocytes, Mononuclear

Share to Polymorphism, Restriction Fragment Length

Share to Protein Tyrosine Phosphatase, Non-Receptor Type 22

Share to Protein Tyrosine Phosphatases

Share to Sex Factors

Source

Identifiers

PMID: 17230194
DOI: 10.1038/sj.gene.6364369

Genes

PTPN22

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Expression of human PTPN22 alleles.PMID 17230194Read ↗

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