Article
[Heterozygosis H63D in patients with steatohepatitis and chronic hepatitis C].
La Clinica terapeutica - 1 Jan 2000
Pulvirenti D, Neri S, Bertino G, Cutuli N, Ignaccolo L, Misseri M, Tsami A, Caruso L
Abstract excerpt
OBJECTIVE: Classic hereditary hemochromatosis is an autosomal recessive iron-overload disorder associated with mutation of the HFE gene. The homozygous genetic defect predisposes to a chain of events that may culminate in severe damage in multiple organs. Pathologic implications of heterozygous defect are still questionable; in fact since these individuals may have slight increases in intra-cellular iron, it has...
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