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Article

[Iron as comorbid factor in chronic hepatitis C].

Medizinische Klinik (Munich, Germany : 1983) - 15 Dec 2003

Erhardt Andreas, Hauck Katarzyna, Häussinger Dieter

Abstract excerpt

Hepatitis C virus infection is often associated with an elevation of iron parameters. Free liver iron causes liver damage and liver fibrosis preferentially through induction of reactive oxygen species. With an allele frequency of 5-10% for the C282Y mutation and 6-30% for the H63D mutation, there is a frequent coincidence of hemochromatosis (HFE) mutations and chronic hepatitis C. There is increasing evidence...

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Source

Identifiers

PMID: 14685669
DOI: 10.1007/s00063-003-1314-5

Genes

HFE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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Common heterozygous hemochromatosis gene mutations are risk factors for inflammation and fibrosis in chronic hepatitis C.Semantic proximity Read ↗

[A study on hepatic iron overload in chronic hepatitis C patients].Semantic proximity Read ↗

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