Article
Role of human leucocyte antigen DQ in the presentation of T cell epitopes in the major cow's milk allergen alphas1-casein.
International archives of allergy and immunology - 1 Jan 2007
Ruiter B, Rozemuller E H, van Dijk A J, Garssen J, Bruijnzeel-Koomen C A F M, Tilanus M G, Knol E F, van Hoffen E
Abstract excerpt
BACKGROUND: Little is known about the association between human leucocyte antigen (HLA) and cow's milk allergy (CMA). The aim of the present study was to determine the HLA restriction of T cell clones (TCCs) specific to alphas1-casein, the most abundant milk protein, and to study possible HLA class II allele associations with CMA. METHODS: alphas1-Casein-specific TCCs were derived from 6 children with CMA, 9...
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