Article
Fine specificity of neonatal lymphocytes to an abundant malaria blood-stage antigen: epitope mapping of Plasmodium falciparum MSP1(33).
Journal of immunology (Baltimore, Md. : 1950) - 1 Mar 2008
Malhotra Indu, Wamachi Alex N, Mungai Peter L, Mzungu Elton, Koech Davy, Muchiri Eric, Moormann Ann M, King Christopher L
Abstract excerpt
Cord blood T cells have been reported to respond to a variety of exogenous Ags, including environmental allergens and various viruses and parasites, as demonstrated by enhanced proliferation and cytokine secretion. This finding is evidence that Ags in the maternal environment transplacentally prime and result in fetal development of memory T cells. Some studies suggest these neonatal T cell responses may arise by...
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