Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Possible involvement of ActVI-ORFA in transcriptional regulation of actVI tailoring-step genes for actinorhodin biosynthesis.

FEMS microbiology letters - 1 Apr 2007

Taguchi Takaaki, Okamoto Susumu, Lezhava Alexander, Li Aiying, Ochi Kozo, Ebizuka Yutaka, Ichinose Koji

Abstract excerpt

The actinorhodin biosynthetic gene (act) cluster in Streptomyces coelicolor carries a functionally unknown gene, actVI-ORFA. We have characterized an ActVI-ORFA disruptant by functional complementation and reverse transcriptase polymerase chain reaction analysis of the expression profiles of the act genes. Introduction of the functional actVI-ORFA gene into the disruptant restored actinorhodin production to an...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anthraquinones
Share to Chromatography, High Pressure Liquid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Culture Media

Share to Gene Expression Regulation, Bacterial

Share to Genes, Bacterial

Share to Multigene Family

Share to Open Reading Frames

Share to Streptomyces

Source

Identifiers

PMID: 17227452
DOI: 10.1111/j.1574-6968.2007.00627.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Possible involvement of ActVI-ORFA in transcriptional regulation of actVI tailoring-step genes for actinorhodin biosynthesis.PMID 17227452Read ↗

DNA sequence and functions of the actVI region of the actinorhodin biosynthetic gene cluster of Streptomyces coelicolor A3(2).Semantic proximity Read ↗

Organisation and functions of the actVA region of the actinorhodin biosynthetic gene cluster of Streptomyces coelicolor.Semantic proximity Read ↗

ActVI-ORFA directs metabolic flux towards actinorhodin by preventing intermediate degradation.Semantic proximity Read ↗

Chemical characterisation of disruptants of the Streptomyces coelicolor A3(2) actVI genes involved in actinorhodin biosynthesis.Semantic proximity Read ↗

Transcriptional activation of the pathway-specific regulator of the actinorhodin biosynthetic genes in Streptomyces coelicolor.Semantic proximity Read ↗

Differential regulation of antibiotic biosynthesis by DraR-K, a novel two-component system in Streptomyces coelicolor.Semantic proximity Read ↗

Functional complementation of pyran ring formation in actinorhodin biosynthesis in Streptomyces coelicolor A3(2) by ketoreductase genes for granaticin biosynthesis.Semantic proximity Read ↗

A putative transglycosylase encoded by SCO4132 influences morphological differentiation and actinorhodin production in Streptomyces coelicolor.Semantic proximity Read ↗

SarA influences the sporulation and secondary metabolism in Streptomyces coelicolor M145.Semantic proximity Read ↗

Identification of the actinorhodin monomer and its related compound from a deletion mutant of the actVA-ORF4 gene of Streptomyces coelicolor A3(2).Semantic proximity Read ↗

Involvement of AlpV, a new member of the Streptomyces antibiotic regulatory protein family, in regulation of the duplicated type II polyketide synthase alp gene cluster in Streptomyces ambofaciens.Semantic proximity Read ↗

afsR is a pleiotropic but conditionally required regulatory gene for antibiotic production in Streptomyces coelicolor A3(2).Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.