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Article

Variant in sex hormone-binding globulin gene and the risk of prostate cancer.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jan 2007

Berndt Sonja I, Chatterjee Nilanjan, Huang Wen-Yi, Chanock Stephen J, Welch Robert, Crawford E David, Hayes Richard B

Abstract excerpt

Sex hormones have been implicated in prostate carcinogenesis and are thought to modulate cell proliferation and growth. To investigate the association between polymorphisms in hormone-related genes and prostate cancer risk, we conducted a two-stage, case-control study within the screening arm of the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial. Using DNA extracted from blood specimens, we...

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Source

Identifiers

PMID: 17220347
DOI: 10.1158/1055-9965.EPI-06-0689

Genes

SHBG
ESR1
GNRH1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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