Comment on "A common genetic variant is associated with adult and childhood obesity".

doi:10.1126/science.1130571

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Comment on "A common genetic variant is associated with adult and childhood obesity".

Science (New York, N.Y.) - 12 Jan 2007

Rosskopf Dieter, Bornhorst Alexa, Rimmbach Christian, Schwahn Christian, Kayser Alexander, Krüger Anne, Tessmann Grietje, Geissler Ingrid, Kroemer Heyo K, Völzke Henry

Abstract excerpt

Contrary to the findings of Herbert et al. (Reports, 14 April 2006, p. 279), homozygous carriers of the C allele of the rs7566605 variant near the INSIG2 gene did not exhibit a significantly increased risk for obesity in a large population-based cross-sectional German study. A subgroup analysis, however, revealed that this allele significantly increased the risk for obesity in already overweight individuals.

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PMID: 17218510
DOI: 10.1126/science.1130571

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INSIG2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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Comment on "A common genetic variant is associated with adult and childhood obesity".PMID 17218510Read ↗

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