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Article

Non-replication of genome-wide based associations between common variants in INSIG2 and PFKP and obesity in studies of 18,014 Danes.

PloS one - 6 Aug 2008

Andreasen Camilla H, Mogensen Mette S, Borch-Johnsen Knut, Sandbaek Annelli, Lauritzen Torsten, Sørensen Thorkild I A, Hansen Lars, Almind Katrine, Jørgensen Torben, Pedersen Oluf, Hansen Torben

Abstract excerpt

BACKGROUND: The INSIG2 rs7566605 and PFKP rs6602024 polymorphisms have been identified as obesity gene variants in genome-wide association (GWA) studies. However, replication has been contradictory for both variants. The aims of this study were to validate these obesity-associations through case-control studies and analyses of obesity-related quantitative traits. Moreover, since environmental and genetic factors...

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Source

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Identifiers

PMID: 18682847
DOI: 10.1371/journal.pone.0002872
PMCID: PMC2483934

Genes

INSIG2
PFKP
FTO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Non-replication of genome-wide based associations between common variants in INSIG2 and PFKP and obesity in studies of 18,014 Danes.PMID 18682847Read ↗

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