Article
Failure to detect MHC class II associations of the human immune response induced by repeated malaria infections to the Plasmodium falciparum antigen Pf155/RESA.
International immunology - 1 Oct 1991
Troye-Blomberg M, Olerup O, Larsson A, Sjöberg K, Perlmann H, Riley E, Lepers J P, Perlmann P
Abstract excerpt
Available evidence suggests that human T and B cell responses to a major Plasmodium falciparum malaria antigen (Pf155/RESA) in individuals primed by repeated infections are genetically regulated. In the present study we have attempted to establish whether these regulations reflect genetic restric...
Topics
- Adult
- Alleles
- Amino Acid Sequence
- Antibodies, Monoclonal
- Antibody Formation
- Epitopes
- Genes, MHC Class II
- Genetics, Population
- HLA Antigens
- Humans
- Lymphocyte Activation
- Malaria, Falciparum
- Male
- Molecular Sequence Data
- Peptides