Article
Failure to detect MHC class II associations of the human immune response induced by repeated malaria infections to the Plasmodium falciparum antigen Pf155/RESA.
International immunology - 1 Oct 1991
Troye-Blomberg M, Olerup O, Larsson A, Sjöberg K, Perlmann H, Riley E, Lepers J P, Perlmann P
Abstract excerpt
Available evidence suggests that human T and B cell responses to a major Plasmodium falciparum malaria antigen (Pf155/RESA) in individuals primed by repeated infections are genetically regulated. In the present study we have attempted to establish whether these regulations reflect genetic restrictions imposed on the immune response by class II molecules of the donor's MHC system. T cell activation (proliferation...
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