Functional deficit of T regulatory cells in Fulani, an ethnic group with low susceptibility to Plasmodium falciparum malaria.

doi:10.1073/pnas.0709969105

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Article

Functional deficit of T regulatory cells in Fulani, an ethnic group with low susceptibility to Plasmodium falciparum malaria.

Proceedings of the National Academy of Sciences of the United States of America - 15 Jan 2008

Torcia Maria G, Santarlasci Veronica, Cosmi Lorenzo, Clemente AnnMaria, Maggi Laura, Mangano Valentina D, Verra Federica, Bancone Germana, Nebie Issa, Sirima Bienvenu Sodiomon, Liotta Francesco, Frosali Francesca, Angeli Roberta, Severini Carlo, Sannella Anna R, Bonini Paolo, Lucibello Maria, Maggi Enrico, Garaci Enrico, Coluzzi Mario, Cozzolino Federico, Annunziato Francesco, Romagnani Sergio, Modiano David

Abstract excerpt

Previous interethnic comparative studies on the susceptibility to malaria performed in West Africa showed that Fulani are more resistant to Plasmodium falciparum malaria than are sympatric ethnic groups. This lower susceptibility is not associated to classic malaria-resistance genes, and the anal...

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Identifiers

PMID: 18174328
DOI: 10.1073/pnas.0709969105
PMCID: PMC2206590

Genes

CTLA4
FOXP3
CCL22
CXCL10
GATA3
TBX21

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18174328-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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