Article
Analysis of the CC chemokine receptor 5 delta32 polymorphism in a Brazilian population with cutaneous leishmaniasis.
Journal of cutaneous pathology - 1 Jan 2007
Brajão de Oliveira Karen, Reiche Edna Maria Vissoci, Kaminami Morimoto Helena, Pelegrinelli Fungaro Maria Helena, Estevão Dirceu, Pontello Rubens, Franco Nasser Thiago, Watanabe Maria Angelica Ehara
Abstract excerpt
Patients with mucocutaneous leishmaniasis (MCL) show a vigorous T-cell immune response against Leishmania braziliensis. Because the Th response is associated with inflammation, the non-functional CC chemokine receptor 5 (CCR5) may rely in a less severe inflammatory state. The aim of this study was to investigate the CCR5 gene in a Brazilian population with leishmaniasis compared with healthy control subjects and...
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